The zoo is raising funds through a crowdfunding campaign over Michigan-based platform Patronicity.
MEDC community development director Katharine Czarnecki said: "This campaign will allow residents, businesses and everyone who appreciates the Zoo and the positive impact it has on Metro Detroit to be a part of this innovative undertaking."
The biodigester will be designed to turn the 400 tons of animal manure generated annually and other organic waste at the zoo, into methane-rich gas.
The biogas will be used to power the 18,000 sq ft Ruth Roby Glancy Animal Health Complex, saving $70-80,000 a year for the zoo in energy costs.
Additionally, the system will convert manure into compost for use as fertilizer at animal habitats, gardens and public spaces throughout the zoo.
DZS executive director and CEO Ron Kagan said: "The biodigester will turn one of our most abundant resources – manure – into energy, and represents a significant step on our green journey."
Construction on the biodigester will begin and be completed this year.