The solar plant stretches across 2,000 acres of federal lands in Clark County managed by the US Bureau of Land Management.
It features more than 3.4 million First Solar thin-film photovoltaic panels that are mounted on single-axis trackers.
The solar plant has the capacity to generate enough clean energy to power about 80,000 homes and reduce 150,000 tonnes of carbon dioxide emissions per year.
NextEra Energy Resources will own and operate the solar energy centre. Starting this year, Southern California Edison will buy the output of the facility under a 20-year contract.
More than 2,100 jobs were created during the construction phase. The facility is estimated to generate more than $78m in property taxes over its operational life.
NextEra Energy Resources president and CEO Armando Pimentel said: "Nevada has plentiful sunshine, and with the Silver State South Solar Energy Center we are harvesting that valuable resource for the benefit of everyone in this region.
"From the jobs and tax revenue it is creating, to the clean energy it will generate over the next 30 years, this is a project that all can take great pride in."
First Solar COO Tymen deJong said: "First Solar's PV technology is setting the standard for generating affordable, clean energy.
"By continuously driving down the cost of solar electricity and providing a solution that addresses energy security and water scarcity, we are delivering on our commitment to build a more sustainable energy future."
